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Prednisone is a cortisteroid and is used in treatment of wide range of serious diseases including some kinds of cancer. In general it is offered in the conditions caused by inadequate hormone production in the body. It is used in treatment of arthritis, psoriasis, asthma, lupus, Crohn’s disease and ulcerative colitis. Many times Prednisone treatment causes suppression of immune system that can make the patient vulnerable for many infectious diseases. If the patient is already having some infections the condition could be aggravated. This requires care to be exercised while administering Prednisone.

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Prednisone is a medication falling in the class called prodrug; it means that drug itself is passive but when is metabolized by liver it gets converted to prednisolone which is an active element and a steroid. It is called “corticosteroid” not to be confused with anabolic steroid that are taken by sportsmen. The drug, due to its action of direct boosting the levels of hormones shows instant results but the very effect can have very severe adverse effects.

Being a potent steroid, prednisone can have serious side effects. It can show symptoms of difficulty in breathing, swelling in mouth, throat and lips and hives; in such cases immediate medical help must be sought. There are other side affects like gain of weight, coughing blood, blurred vision and pancreatitis. It can also cause confusion and uneven heart beat or dangerous increase in blood pressure. Acne, sweating, dizziness, dry skin and nausea are the side effects but these are not considered as serious.

Prednisone is available in different dosages of tablets from 2.5 mg to 50 mg. It is also available as oral administered syrup. For adults it is given in dosage of 5mg PO in morning and .5 mg in evening. For children it can be given 4 to 5 mg per day. Higher dosages are used in treatment of cancer along with other cancer medication. The dosage is determined by the condition of the patient, severity of disease and also based on the other drugs which the patient is taking.

When the drug is taken for more than seven days it affects the natural production of hormones including adrenal. The suppression of adrenal has serious consequences and this is the common result of taking all cortisols. This makes the patient dependent on prednisone.
It is necessary not to abruptly stop prednisone after taking more than a week. The dosage must be truncated till the patient regains the normal production of hormones and some times it can be a long period.

Though Prednisone is used in treatment of many types of serious conditions care must be exercised in its use regarding the adverse effects caused by immunosuppression and development of dependency.